Bogdanov T.G., Hikov T.A., Sabit Z.A., Tafradzhiyska-Hadzhiolova R., Pencheva D.T. Development of a 3D-Printed Wistar Rat Model From Digital Imaging and Communications in Medicine (DICOM) Data for Medical Education and Research Applications. Cureus. 2025 Jan 26;17(1):e78012. doi: 10.7759/cureus.78012

PMID: 40034894

Abstract

Three-dimensional (3D) printing has revolutionized medical education and research by enabling the creation of accurate anatomical models derived from imaging studies. This report details the development of a 3D-printed Wistar rat model, produced using DICOM (Digital Imaging and Communications in Medicine) data from a single radiological study. The model was designed to serve as an educational tool for medical and veterinary students and as a resource for researchers.

DICOM data from a single animal study was segmented and converted into a high-resolution 3D model using specialized software that converts the voxels from the slices into a waterfall volume with a uniform surface. The resulting STL file underwent optimization to ensure compatibility with common 3D printing technologies, such as fused deposition modeling (FDM) and stereolithography (SLA). The final printed model replicates the intricate anatomical details of the Wistar rat, providing a valuable aid for studying rodent anatomy and simulating procedures in preclinical research.

The STL file is freely accessible to researchers and educators, promoting the adoption of 3D-printed models in academic settings. Providing open access to this model, we aim to enable researchers, educators, and clinicians worldwide to utilize it for various purposes, including comparative anatomy studies, surgical training, and educational demonstrations. This approach significantly enhances the usability of our findings and fosters collaboration across disciplines, making the model a valuable resource for the scientific community. By integrating advanced imaging techniques with 3D printing, this study demonstrates a cost-effective and scalable approach to enhancing medical education and research capabilities.